The purpose of this research was to determine the mediating role of integrative self-knowledge in the relationship between family emotional atmosphere and self-control among high school students in Naqadeh. This research had a descriptive design. The statistical population of the study was comprised of all senior high school students in Naqadeh in 2018-19 school year. The drawn sample (315 students) was selected via cluster random sampling method. The instruments included the Integrative Self-Knowledge Scale (Ghorbani et al., 2008), Family Emotional Condition Questionnaire (Hill Burn, 1964) and a Self-Control Scale (Tangney et al., 2004). Data analysis was performed utilizing structural equation modeling method in PLS3 program. The findings showed a positive, significant relationship between family emotional atmosphere, integrative self-knowledge, and self-control. Results also indicated that integrative self-knowledge played a mediating role in the link between family emotional atmosphere and self-control. Furthermore, the results demonstrated that the level of students' self-control was greatly correlated with family emotional atmosphere and integrative self-knowledge. Based on the research findings, it is suggested that family emotional atmosphere be addressed in interventions designed for the promotion of self-control and self-knowledge.